Expression and prognostic analysis of Rho GTPase-activating protein 11A in lung adenocarcinoma.

ABSTRACT:

Background

Rho GTPase-activating protein 11A (ARHGAP11A) is a member of the Rho GTPase-activating protein (RhoGAP) subfamily. However, its expression, prognostic significance and clinicopathologic factors correlation in lung adenocarcinoma is still unclear.

Methods

The original gene expression profile, survival data, and clinical information of patients with lung adenocarcinoma (LUAD) were downloaded from The Cancer Genome Atlas (TCGA) database. The expression difference of ARHGAP11A between LUAD tissues and adjacent normal tissues in the TCGA database was analyzed by using R software, and verified by the Oncomine database and immunohistochemical (IHC) assay of LUAD sections. Logistic regression was applied to analyze the relationship between the expression of ARHGAP11A and

SUBMITTER: Chen S 

PROVIDER: S-EPMC8184474 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature