Endophthalmitis Prophylaxis Failures in Patients Injected With Intracameral Antibiotic During Cataract Surgery.

ABSTRACT:

Purpose

To estimate the association of cefuroxime and moxifloxacin in relation to the occurrence of endophthalmitis following phacoemulsification cataract surgery.

Design

Retrospective clinical cohort study.

Methods

We studied patients with noncomplex phacoemulsification cataract surgery in Kaiser Permanente Northern California during 2014-2019. Data were obtained for acute, postoperative endophthalmitis within 90 days of phacoemulsification, including culture and antibiogram results, intracameral and topical antibiotic agent, and dose. In a post hoc analysis, we also examined preoperative anterior chamber depth (ACD) and postoperative anterior chamber volume (ACV).

Results

Of 216,141 surgeries, endophthalmitis occurred in 0.020% of moxifloxacin-injected eyes a

SUBMITTER: Shorstein NH 

PROVIDER: S-EPMC8184599 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature