Regional brain morphology predicts pain relief in trigeminal neuralgia.

ABSTRACT:

Background

Trigeminal neuralgia, a severe chronic neuropathic pain disorder, is widely believed to be amenable to surgical treatments. Nearly 20% of patients, however, do not have adequate pain relief after surgery. Objective tools for personalized pre-treatment prognostication of pain relief following surgical interventions can minimize unnecessary surgeries and thus are of substantial benefit for patients and clinicians.

Purpose

To determine if pre-treatment regional brain morphology-based machine learning models can prognosticate 1 year response to Gamma Knife radiosurgery for trigeminal neuralgia.

Methods

We used a data-driven approach that combined retrospective structural neuroimaging data and support vector machine-based machine learning to produce robust multi

SUBMITTER: Hung PS 

PROVIDER: S-EPMC8184658 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature