Prevalence and prognostic value of cardiac troponin in elderly patients hospitalized for COVID-19.

ABSTRACT:

Background

Increases in cardiac troponin (cTn) in coronavirus disease 2019 (COVID-19) have been associated with worse prognosis. Nonetheless, data about the significance of cTn in elderly subjects with COVID-19 are lacking.

Methods

From a registry of consecutive patients with COVID-19 admitted to a hub hospital in Italy from 25/02/2020 to 03/07/2020, we selected those ≥ 60 year-old and with cTnI measured within three days from the molecular diagnosis of SARS-CoV-2 infection. When available, a second cTnI value within 48 h was also extracted. The relationship between increased cTnI and all-cause in-hospital mortality was evaluated by a Cox regression model and restricted cubic spline functions with three knots.

Results

Of 343 included patients (median age: 75.0 (68.0-8

SUBMITTER: De Marzo V 

PROVIDER: S-EPMC8185447 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature