Innervation of the Human Intervertebral Disc: A Scoping Review.

ABSTRACT:

Objective

Back pain is an elusive symptom complicated by a variety of possible causes, precipitating and maintaining factors, and consequences. Notably, the underlying pathology remains unknown in a significant number of cases. Changes to the intervertebral disc (IVD) have been associated with back pain, leading many to postulate that the IVD may be a direct source of pain, typically referred to as discogenic back pain. Yet despite decades of research into the neuroanatomy of the IVD, there is a lack of consensus in the literature as to the distribution and function of neural elements within the tissue. The current scoping review provides a comprehensive systematic overview of studies that document the topography, morphology, and immunoreactivity of neural elements within the IVD i

SUBMITTER: Groh AMR 

PROVIDER: S-EPMC8185559 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature