Role of lymph node dissection at the time of open or minimally invasive nephroureterectomy.

ABSTRACT: Unlike urothelial carcinoma of the bladder, there is no guideline-based consensus on whether a lymph node dissection (LND) should be performed at the time of radical nephroureterectomy (RNU) for upper tract urothelial carcinoma (UTUC). Variable lymphatic drainage based on primary tumor location, lack of prospective trials, and difficulties in developing a risk-adapted approach to LND for UTUC are all challenges to the development of an established approach. The UTUC literature consists of an evidence pool that has historically been limited to single-institution series with heterogenous inclusion criteria for LND and variable LND templates. Areas of controversy exist regarding migration to the great vessel LN beds for mid and distal tumors. A lack of template standardization limits the inte

SUBMITTER: McIntosh AG 

PROVIDER: S-EPMC8185683 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature