Filaricidal activity of Daniellia oliveri and Psorospermum febrifugum extracts.

ABSTRACT:

Background

Drugs currently used for controlling onchocerciasis and lymphatic filariasis (LF) are mainly microfilaricidal, with minimal or no effect on the adult worms. For efficient management of these diseases, it is necessary to search for new drugs with macrofilaricidal activities that can be used singly or in combination with existing ones. Daniellia oliveri and Psorospermum febrifugum are two plants commonly used in the local management of these infections in Bambui, a township in the North West Region of Cameroon, but there is currently no documented scientific evidence to support their claimed anthelmintic efficacy and safety. The aim of this study was to provide evidence in support of the search for means to eliminate these diseases by screening extracts and chromatographic

SUBMITTER: Abongwa M 

PROVIDER: S-EPMC8186089 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature