3D quantitative analysis of diffusion-weighted imaging for predicting the malignant potential of intraductal papillary mucinous neoplasms of the pancreas.

ABSTRACT:

Purpose

To investigate the predictors of intraductal papillary mucinous neoplasms of the pancreas (IPMNs) with high-grade dysplasia, using 2-dimensional (2D) analysis and 3-dimensional (3D) volume-of-interest-based apparent diffusion coefficient (ADC) histogram analysis.

Material and methods

The data of 45 patients with histopathologically confirmed IPMNs with high-grade or low-grade dysplasia were retrospectively assessed. The 2D analysis included lesion-to-spinal cord signal intensity ratio (LSR), minimum ADC value (ADC_min), and mean ADC value (ADC_mean). The 3D analysis included the overall mean (ADC_{overall mean}), mean of the bottom 10^th percentile (ADC_mean0-10), mean of the bottom 10-25^th percentile (ADC

SUBMITTER: Igarashi T 

PROVIDER: S-EPMC8186307 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature