Genome wide association study for the identification of genes associated with tail fat deposition in Chinese sheep breeds.

ABSTRACT: Chinese indigenous sheep can be classified into three types based on tail morphology: fat-tailed, fat-rumped, and thin-tailed sheep, of which the typical breeds are large-tailed Han sheep, Altay sheep, and Tibetan sheep, respectively. To unravel the molecular genetic basis underlying the phenotypic differences among Chinese indigenous sheep with these three different tail types, we used ovine high-density 600K single nucleotide polymorphism (SNP) arrays to detect genome-wide associations, and performed general linear model analysis to identify candidate genes, using genotyping technology to validate the candidate genes. Tail type is an important economic trait in sheep. However, the candidate genes associated with tail type are not known. The objective of this study was to identify SNP mar

SUBMITTER: Zhu C 

PROVIDER: S-EPMC8186729 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature