Oxytocin-Trust Link in Oxytocin-Sensitive Participants and Those Without Autistic Traits.

ABSTRACT: There have been numerous studies in which the biological role of oxytocin in trusting behavior has been investigated. However, a link between oxytocin and trust in humans was discovered only in one early study. We hypothesized that there is a large interindividual variation in oxytocin sensitivity, and that such variation is one reason for the doubt surrounding the role of oxytocin in trusting behavior. Here, in a double-blind, prospective, case-control study, we administered intranasal oxytocin to participants of trust and risk games. We measured salivary oxytocin concentration, relating it to the amount of money transferred among participants (a proxy for trust) and the autism-spectrum quotient (AQ). A one-sided Fisher's exact test was performed to detect differences between the oxytocin

SUBMITTER: Kurokawa H 

PROVIDER: S-EPMC8186783 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature