Blood culture negative infective endocarditis in adult congenital heart disease patients with prosthetic grafts: a case series.

ABSTRACT:

Background

Blood culture negative infective endocarditis (BCNIE) is often a diagnostic challenge in adult congenital heart disease patients leading to misdiagnosis, treatment delay and associated high mortality. Studies of BCNIE in adult congenital heart disease patients repaired with prosthetic cardiovascular grafts are limited.

Case summary

We report two cases of BCNIE where serology testing, multiple polymerase chain reaction testing of explanted valve material and multi-modality imaging including ¹⁸F-fluorodeoxyglucose positron emission tomography/computed tomography (¹⁸F-FDG PET/CT) were utilized not only to confirm the diagnosis but also to guide management strategy and inform prognosis. Both patients were treated successfully with cardiac surgery

SUBMITTER: Lwin MT 

PROVIDER: S-EPMC8186933 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature