The impact of parental risk factors on the risk of stroke in type 1 diabetes.

ABSTRACT:

Background

Individuals with type 1 diabetes have a markedly increased risk of stroke. In the general population, genetic predisposition has been linked to increased risk of stroke, but this has not been assessed in type 1 diabetes. Our aim was, therefore, to study how parental risk factors affect the risk of stroke in individuals with type 1 diabetes.

Methods

This study represents an observational follow-up of 4011 individuals from the Finnish Diabetic Nephropathy Study, mean age at baseline 37.6 ± 11.9 years. All strokes during follow-up were verified from medical records or death certificates. The strokes were classified as either ischemic or hemorrhagic. All individuals filled out questionnaires concerning their parents' medical history of hypertension, diabetes, stroke,

SUBMITTER: Ylinen A 

PROVIDER: S-EPMC8187180 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature