Frailty subtypes and recovery in older survivors of acute respiratory failure: a pilot study.

ABSTRACT:

Background

Identifying subtypes of acute respiratory failure survivors may facilitate patient selection for post-intensive care unit (ICU) follow-up clinics and trials.

Methods

We conducted a single-centre prospective cohort study of 185 acute respiratory failure survivors, aged ≥ 65 years. We applied latent class modelling to identify frailty subtypes using frailty phenotype and cognitive impairment measurements made during the week before hospital discharge. We used Fine-Gray competing risks survival regression to test associations between frailty subtypes and recovery, defined as returning to a basic Activities of Daily Living disability count less than or equal to the pre-hospitalisation count within 6 months. We characterised subtypes by pre-ICU frailty (Clinical Frailt

SUBMITTER: Baldwin MR 

PROVIDER: S-EPMC8187474 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature