Ontology highlight
ABSTRACT:
SUBMITTER: Niles MA
PROVIDER: S-EPMC8187925 | biostudies-literature | 2021
REPOSITORIES: biostudies-literature
Niles Marc A MA Gogesch Patricia P Kronhart Stefanie S Ortega Iannazzo Samira S Kochs Georg G Waibler Zoe Z Anzaghe Martina M
Frontiers in immunology 20210526
The exact role of innate immune cells upon infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and their contribution to the formation of the corona virus-induced disease (COVID)-19 associated cytokine storm is not yet fully understood. We show that human <i>in vitro</i> differentiated myeloid dendritic cells (mDC) as well as M1 and M2 macrophages are susceptible to infection with SARS-CoV-2 but are not productively infected. Furthermore, infected mDC, M1-, and M2 macroph ...[more]