Does study subject diversity influence cardiology research site performance?: Insights from 2 U.S. National Coronary Stent Registries.

ABSTRACT:

Background

Minorities and women are underrepresented in cardiovascular research. Whether their higher enrollment can be predicted or influences research site performance is unclear.

Methods

We evaluated 104 sites that enrolled 4,184 patients in the U.S. Platinum Diversity (PD) and Promus Element Plus (PE Plus) studies (2012 to 2016). Research sites were ranked from lowest to highest minority and female enrollment, respectively. United States Census Bureau division and core-based statistical area (CBSA) populations were determined for each site and the following study performance metrics compared across quartiles of minority and female enrollment, respectively: (1) study subject enrollment rate (SER), (2) time to first patient enrolled, (3) rate of follow-up visits not done,

SUBMITTER: Batchelor WB 

PROVIDER: S-EPMC8188231 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature