Low dose statins improve prognosis of ischemic stroke patients with intravenous thrombolysis.

ABSTRACT:

Background

For acute ischaemic stroke patients, it is uncertain whether intravenous thrombolysis combined with statins might increase the therapeutic effect. Additionally, using high-intensity statins after thrombolysis may increase the risk of bleeding in patients. Asian stroke patients often take low-dose statins. It is speculated that reducing the dose of statins may improve the risk of bleeding.

Methods

Data from consecutive acute ischaemic stroke patients with intravenous thrombolysis were prospectively collected. Efficacy outcomes included NIHSS (National Institutes of Health Stroke Scale) score improvement at 7 days after admission and mRS (Modified Rankin Scale) improvement at 90 days. Safety outcomes included haemorrhage events (intracerebral haemorrhage and gastroi

SUBMITTER: Cui C 

PROVIDER: S-EPMC8188651 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature