Association of perioperative serum carcinoembryonic antigen level and recurrence in low-risk stage IIA colon cancer.

ABSTRACT:

Background

The purpose is to investigate prognosis according to serum CEA levels before and after surgery in patients with stage IIA colon cancer who do not show high-risk features.

Methods

Among the patients diagnosed with colon adenocarcinoma between April 2011 and December 2017, 462 patients were confirmed as low-risk stage IIA after surgery and enrolled. The ROC curve was used to determine cut-off values of pre- and postoperative CEA. Patients were classified into three groups using these new cut-off values.

Results

All recurrence occurred in 52 of 463 patients (11.2%). However, recurrence in group H was 15.9%, which was slightly higher than the other two groups (P = 0.04). Group L and M showed 10.5% and 12.8% overall survival, group H was higher at 21.0% (P = 0.0

SUBMITTER: Kim HG 

PROVIDER: S-EPMC8189445 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature