MultipleTesting.com: A tool for life science researchers for multiple hypothesis testing correction.

ABSTRACT: Scientists from nearly all disciplines face the problem of simultaneously evaluating many hypotheses. Conducting multiple comparisons increases the likelihood that a non-negligible proportion of associations will be false positives, clouding real discoveries. Drawing valid conclusions require taking into account the number of performed statistical tests and adjusting the statistical confidence measures. Several strategies exist to overcome the problem of multiple hypothesis testing. We aim to summarize critical statistical concepts and widely used correction approaches while also draw attention to frequently misinterpreted notions of statistical inference. We provide a step-by-step description of each multiple-testing correction method with clear examples and present an easy-to-follow guid

SUBMITTER: Menyhart O 

PROVIDER: S-EPMC8189492 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature