Dysnatremia and 6-Month Functional Outcomes in Critically Ill Patients With Aneurysmal Subarachnoid Hemorrhage: A Prospective Cohort Study.

ABSTRACT:

Objectives

To investigate the association between plasma sodium concentrations and 6-month neurologic outcome in critically ill patients with aneurysmal subarachnoid hemorrhage.

Design

Prospective cohort study.

Setting

Eleven ICUs in Australia and New Zealand.

Participants

Three-hundred fifty-six aneurysmal subarachnoid hemorrhage patients admitted to ICU between March 2016 and June 2018. The exposure variable was daily measured plasma sodium.

Interventions

None.

Measurements and main results

Six-month neurologic outcome as measured by the modified Rankin Scale. A poor outcome was defined as a modified Rankin Scale greater than or equal to 4. The mean age was 57 years (± 12.6 yr), 68% were female, and 32% (n = 113) had a poor outcome. In mu

SUBMITTER: Cohen J 

PROVIDER: S-EPMC8189636 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature