Prediction of Early Recanalization after Intravenous Thrombolysis in Patients with Large-Vessel Occlusion.

ABSTRACT:

Background and purpose

We aimed to develop a model predicting early recanalization after intravenous tissue plasminogen activator (t-PA) treatment in large-vessel occlusion.

Methods

Using data from two different multicenter prospective cohorts, we determined the factors associated with early recanalization immediately after t-PA in stroke patients with large-vessel occlusion, and developed and validated a prediction model for early recanalization. Clot volume was semiautomatically measured on thin-section computed tomography using software, and the degree of collaterals was determined using the Tan score. Follow-up angiographic studies were performed immediately after t-PA treatment to assess early recanalization.

Results

Early recanalization, assessed 61.0±44.7 minut

SUBMITTER: Kim YD 

PROVIDER: S-EPMC8189851 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature