Ontology highlight
ABSTRACT:
SUBMITTER: Shi X
PROVIDER: S-EPMC8190037 | biostudies-literature | 2021 Jun
REPOSITORIES: biostudies-literature
Shi Xiaoguang X Ren Shuanglai S Zhang Bingying B Guo Shanshan S He Wenxin W Yuan Chengmin C Yang Xiaofan X Ig-Lzevbekhai Kevin K Sun Tao T Wang Qinwen Q Cui Jianqi J
Scientific reports 20210609 1
Purine rich element binding protein A (Purα), encoded by the Purα gene, is an important transcriptional regulator that binds to DNA and RNA and is involved in processes such as DNA replication and RNA translation. Purα also plays an important role in the nervous system. To identify the function of Pura, we performed RNA sequence (RNA-seq) analysis of Purɑ-KO mouse hippocampal neuron cell line (HT22) to analyze the effect of Purα deletion on neuronal expression profiles. And combined with ChIP-se ...[more]