Primary tumor resection improves survival in patients with multifocal intrahepatic cholangiocarcinoma based on a population study.

ABSTRACT: The purpose of our study was to evaluate the effect of surgery on the survival and prognosis of patients with multifocal intrahepatic cholangiocarcinoma (ICCA). Patients with multifocal ICCA were selected from the SEER (Surveillance, Epidemiology, and End Results) database between 2010 and 2016. Kaplan-Meier analyses and log-rank tests were used to evaluate the difference in survival between the surgery group and the non-surgery group. We applied the Cox proportional hazards regression model to identify prognostic factors of overall survival (OS) and cancer-specific survival (CSS). In total, 580 patients were enrolled in our study, including 151 patients who underwent surgery and 429 patients who did not. The median survival time of surgical patients was longer than non-surgical patients (

SUBMITTER: Yin L 

PROVIDER: S-EPMC8190174 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature