Large-scale open-source three-dimensional growth curves for clinical facial assessment and objective description of facial dysmorphism.

ABSTRACT: Craniofacial dysmorphism is associated with thousands of genetic and environmental disorders. Delineation of salient facial characteristics can guide clinicians towards a correct clinical diagnosis and understanding the pathogenesis of the disorder. Abnormal facial shape might require craniofacial surgical intervention, with the restoration of normal shape an important surgical outcome. Facial anthropometric growth curves or standards of single inter-landmark measurements have traditionally supported assessments of normal and abnormal facial shape, for both clinical and research applications. However, these fail to capture the full complexity of facial shape. With the increasing availability of 3D photographs, methods of assessment that take advantage of the rich information contained in s

SUBMITTER: Matthews HS 

PROVIDER: S-EPMC8190313 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature