Does quantity equal quality?-A morphokinetic assessment of embryos obtained from young women with decreased ovarian response to controlled ovarian stimulation.

ABSTRACT:

Purpose

To assess oocyte quality in young patients with decreased ovarian response to controlled ovarian stimulation using time-lapse analysis.

Methods

A retrospective cohort study conducted at five medical centers between 2013 and 2017. The "decreased ovarian response" (DOR) group consisted of 241 women who underwent controlled ovarian stimulation with ≤ 5 retrieved oocytes and 519 cultured embryos. The "normal response" (NOR) group consisted of 667 women with ≥ 6 retrieved oocytes resulting in 3633 embryos. Data included annotation of morphokinetic events of embryos cultured in a time-lapse incubator from time of pronuclei appearance to time of starting blastocyst formation (tSB). Comparison was made between morphokinetic parameters of DOR and NOR patients with additional

SUBMITTER: Schachter-Safrai N 

PROVIDER: S-EPMC8190327 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature