Effective HPV vaccination coverage in Australia by number of doses and two-dose spacing: What if one or two doses are sufficient?

ABSTRACT:

Background

Initially, three-dose schedules were recommended for vaccines against human papillomavirus (HPV); subsequently recommendations have been updated to a schedule of two doses delivered at least six (minimum five) months apart for those aged <15 years at dose 1. We aimed to re-estimate effective HPV vaccination coverage in Australia, considering reduced-dose schedules and possible one-dose effectiveness. We also aimed to identify which of the three school visits was most commonly missed amongst two-dose only recipients, to inform optimal timing of visits.

Methods

National vaccination register data were used to estimate: i) vaccination coverage at December 2017, either with a complete course (three or two sufficiently-spaced doses (>151 days apart)), or at least one do

SUBMITTER: Smith MA 

PROVIDER: S-EPMC8190554 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature