Comprehensive in silico survey of the Mycolicibacterium mobilome reveals an as yet underexplored diversity.

ABSTRACT: The mobilome plays a crucial role in bacterial adaptation and is therefore a starting point to understand and establish the gene flow occurring in the process of bacterial evolution. This is even more so if we consider that the mobilome of environmental bacteria can be the reservoir of genes that may later appear in the clinic. Recently, new genera have been proposed in the family Mycobacteriaceae, including the genus Mycolicibacterium, which encompasses dozens of species of agricultural, biotechnological, clinical and ecological importance, being ubiquitous in several environments. The current scenario in the Mycobacteriaceae mobilome has some bias because most of the characterized mycobacteriophages were isolated using a single host strain, and the few plasmids repor

SUBMITTER: Morgado SM 

PROVIDER: S-EPMC8190616 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature