Association of Diet Quality With Prevalence of Clonal Hematopoiesis and Adverse Cardiovascular Events.

ABSTRACT:

Importance

Clonal hematopoiesis of indeterminate potential (CHIP), the expansion of somatic leukemogenic variations in hematopoietic stem cells, has been associated with atherosclerotic cardiovascular disease. Because the inherited risk of developing CHIP is low, lifestyle elements such as dietary factors may be associated with the development and outcomes of CHIP.

Objective

To examine whether there is an association between diet quality and the prevalence of CHIP.

Design, setting, and participants

This retrospective cohort study used data from participants in the UK Biobank, an ongoing population-based study in the United Kingdom that examines whole-exome sequencing data and survey-based information on health-associated behaviors. Individuals from the UK Biobank were

SUBMITTER: Bhattacharya R 

PROVIDER: S-EPMC8190703 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature