The association of lipoprotein(a) and intraplaque neovascularization in patients with carotid stenosis: a retrospective study.

ABSTRACT:

Background

Lipoprotein(a) is genetically determined and increasingly recognized as a major risk factor for arteriosclerotic cardiovascular disease. We examined whether plasma lipoprotein(a) concentrations were associated with intraplaque neovascularization (IPN) grade in patients with carotid stenosis and in terms of increasing plaque susceptibility to haemorrhage and rupture.

Methods

We included 85 patients diagnosed with carotid stenosis as confirmed using carotid ultrasound who were treated at Guangdong General Hospital. Baseline data, including demographics, comorbid conditions and carotid ultrasonography, were recorded. The IPN grade was determined using contrast-enhanced ultrasound through the movement of the microbubbles. Univariate and multivariate binary logistic re

SUBMITTER: Xia S 

PROVIDER: S-EPMC8190836 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature