PEG-Neridronate-Modified NaYF₄:Gd³⁺,Yb³⁺,Tm³⁺/NaGdF₄ Core-Shell Upconverting Nanoparticles for Bimodal Magnetic Resonance/Optical Luminescence Imaging.

ABSTRACT: Upconverting nanoparticles are attracting extensive interest as a multimodal imaging tool. In this work, we report on the synthesis and characterization of gadolinium-enriched upconverting nanoparticles for bimodal magnetic resonance and optical luminescence imaging. NaYF₄:Gd³⁺,Yb³⁺,Tm³⁺ core upconverting nanoparticles were obtained by a thermal coprecipitation of lanthanide oleate precursors in the presence of oleic acid as a stabilizer. With the aim of improving the upconversion emission and increasing the amount of Gd³⁺ ions on the nanoparticle surface, a 2.5 nm NaGdF₄ shell was grown by the epitaxial layer-by-layer strategy, resulting in the 26 nm core-shell nanoparticles. Both core and core-shell nanoparticles were coat

SUBMITTER: Kostiv U 

PROVIDER: S-EPMC8190901 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature