50 week ultrasound imaging and ultrastructural abnormalities of bladder after sugar diuresis and diabetes mellitus in rats.

ABSTRACT:

Purpose

To investigate 50 week ultrasound imaging and ultrastructure changes of bladder in diuresis and diabetes rats.

Methods

Forty-two healthy male Sprague-Dawley rats were randomly divided into control group, sugar-induced diuresis group and streptozotocin-induced diabetes group. The 24 h drinking and urine volume were calculated from 21 to 31 weeks. Using ultrasound to assess bladders after 49 weeks. Bladders were examined by transmission electron microscope after 50 weeks.

Results

The drinking and urine volume significantly increased in the diuresis and diabetes groups. The bladder morphology and bladder wall thickness increased in the diuresis and diabetes groups. Bladder stones, bladder overdistension and urinary retention were seen in the diuresis and diabetes

SUBMITTER: Yang K 

PROVIDER: S-EPMC8190992 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature