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Factors related to retinal nerve fiber layer thickness in bipolar disorder patients and major depression patients.


ABSTRACT:

Background

We analyzed the correlation of the clinical data with retinal nerve fiber layer (RNFL) thickness and macular thickness in bipolar disorder patients and major depression patients. The aim of this study is to explore factors that affect RNFL thickness in bipolar disorder patients and major depression patients, with a view to providing a new diagnostic strategy.

Methods

Eighty-two bipolar disorder patients, 35 major depression patients and 274 people who were age and gender matched with the patients were enrolled. Demographic information and metabolic profile of all participants were collected. Best-corrected visual acuity of each eye, intraocular pressure (IOP), fundus examination was performed. RNFL and macular thickness were measured by optical coherence tomograph

SUBMITTER: Liu Y 

PROVIDER: S-EPMC8191183 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature