Norovirus in health care and implications for the immunocompromised host.

ABSTRACT:

Purpose of review

The majority of norovirus outbreaks in the United States occur in healthcare facilities. With the growing population of immunocompromised hosts who are in frequent contact with healthcare facilities, norovirus is not only a threat to hospitals and nursing homes but also to these individuals. This review summarizes the impact of norovirus infection on healthcare facilities and immunocompromised hosts.

Recent findings

The natural history of norovirus infection in immunocompromised individuals remains poorly understood. Although host immune responses play a critical role in reducing duration of viral shedding and viral load in norovirus-infected individuals, why some immunocompromised patients spontaneously recover while others develop a chronic and protracted

SUBMITTER: Chong PP 

PROVIDER: S-EPMC8191235 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature