An alginate-confined peroxygenase-CLEA for styrene epoxidation.
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ABSTRACT:
SUBMITTER: Nintzel FEH
PROVIDER: S-EPMC8191455 | biostudies-literature | 2021 Jun
REPOSITORIES: biostudies-literature
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An alginate-confined peroxygenase-CLEA for styrene epoxidation.
Nintzel Friederike E H FEH Wu Yinqi Y Planchestainer Matteo M Held Martin M Alcalde Miguel M Hollmann Frank F
Chemical communications (Cambridge, England) 20210601 47
Oxyfunctionalisation reactions in neat substrate still pose a challenge for biocatalysis. Here, we report an alginate-confined peroxygenase-CLEA to catalyse the enantioselective epoxidation of cis-β-methylstyrene in a solvent-free reaction system achieving turnover numbers of 96 000 for the biocatalyst and epoxide concentrations of 48 mM. ...[more]
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