Karnofsky Performance Score-Failure to Thrive as a Frailty Proxy?

ABSTRACT: Among patients listed for kidney transplantation, the Karnofsky Performance Status (KPS) Scale has been used as a proxy for frailty and proposed as a predictor of long-term posttransplant outcomes. The KPS is required by the Organ Procurement and Transplantation Network for all transplants; however, the interrater reliability of KPS reporting in kidney transplant candidates has not been well investigated, and there is concern regarding limitations of using KPS that may influence transplant eligibility.

Methods

We performed an observational study using existing Scientific Registry of Transplant Recipients data from 2006 to 2020 to examine the variability, reliability, and trends in the KPS among patients on the kidney transplant waitlist.

Results

Our analysis included 8197 kid

SUBMITTER: Stedman MR 

PROVIDER: S-EPMC8191697 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature