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Prognostic value of preoperative circulating tumor cells counts in patients with UICC stage I-IV colorectal cancer.


ABSTRACT: Colorectal cancer (CRC) is one of the leading causes of cancer death worldwide. There is an urgent need to identify prognostic markers for patients undergoing curative resection of CRC. The detection of circulating tumor cells in peripheral blood is a promising approach to identify high-risk patients with disseminated disease in colorectal cancer. This study aims to evaluate the prognostic relevance of preoperative CTCs using the Cellsearch® system (CS) in patients, who underwent resection with curative intent of different stages (UICC I-IV) of colorectal cancer. Out of 91 Patients who underwent colorectal resection, 68 patients were included in this study. CTC analysis was performed in patients with CRC UICC stages I-IV immediately before surgery. Data were correlated with clinicopatholog

SUBMITTER: Abdalla TSA 

PROVIDER: S-EPMC8191913 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature