Metabolomic Markers of Southern Dietary Patterns in the Jackson Heart Study.

ABSTRACT:

Scope

New biomarkers are needed that are representative of dietary intake.

Methods and results

We assess metabolites associated with Southern dietary patterns in 1401 Jackson Heart Study participants. Three dietary patterns are empirically derived using principal component analysis: meat and fast food, fish and vegetables, and starchy foods. We randomly select two subsets of the study population: two-third sample for discovery (n = 934) and one-third sample for replication (n = 467). Among the 327 metabolites analyzed, 14 are significantly associated with the meat and fast food dietary pattern, four are significantly associated with the fish and vegetables dietary pattern, and none are associated with the starchy foods dietary pattern in the discovery sample. In the replicat

SUBMITTER: Rebholz CM 

PROVIDER: S-EPMC8192080 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature