Long-Acting Injection and Implant Preferences and Trade-Offs for HIV Prevention Among South African Male Youth.

ABSTRACT:

Background

Long-acting pre-exposure prophylaxis (LA-PrEP) formulated as implants and injections are promising prevention method strategies offering simplicity, discretion, and long dose duration. Men are important end users of LA-PrEP, and early assessment of their preferences could enhance downstream male engagement in HIV prevention.

Methods

A discrete-choice experiment survey was conducted with 406 men, aged 18-24, in Cape Town, South Africa, to assess preferences for 5 LA-PrEP attributes with 2-4 pictorially-depicted levels: delivery form, duration, insertion location, soreness, and delivery facility. Latent class analysis was used to explore heterogeneity of preferences and estimate preference shares.

Results

The median age was 21 (interquartile range 19-22), and

SUBMITTER: Montgomery ET 

PROVIDER: S-EPMC8192422 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature