Outcomes After Second-Line Antiretroviral Therapy in Children Living With HIV in Latin America.

ABSTRACT:

Background

Little is known about the long-term outcomes of children living with HIV in Latin America. Few studies have examined antiretroviral therapy (ART) regimen switches in the years after the introduction of ART in this population. This study aimed to assess clinical outcomes among children who started second-line ART in the Caribbean, Central and South America network for HIV epidemiology.

Methods

Children (<18 years old) with HIV who switched to second-line ART at sites within Caribbean, Central and South America network for HIV epidemiology were included. The cumulative incidence and relative hazards of virologic failure while on second-line ART, loss to follow-up, additional major ART regimen changes, and all-cause mortality were evaluated using competing risks meth

SUBMITTER: Somerville K 

PROVIDER: S-EPMC8192432 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature