Influence of cardiovascular risk-factors on morphological changes of cerebral arteries in healthy adults across the life span.

ABSTRACT: Cerebral artery morphological alterations have been associated with several cerebrovascular and neurological diseases, whereas these structures are known to be highly variable among healthy individuals. To date, the knowledge about the influence of cardiovascular risk factors on the morphology of cerebral arteries is rather limited. The aim of this work was to investigate the impact of cardiovascular risk factors on the regional cerebroarterial radius and density. Time-of-Flight magnetic resonance angiography from 1722 healthy adults (21-82 years) were used to extract region-specific measurements describing the main cerebral artery morphology. Multivariate statistical analysis was conducted to quantify the impact of cardiovascular risk factors, including clinical and life behavioural facto

SUBMITTER: Mouches P 

PROVIDER: S-EPMC8192575 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature