Ontology highlight
ABSTRACT:
SUBMITTER: Yang X
PROVIDER: S-EPMC8192703 | biostudies-literature | 2021
REPOSITORIES: biostudies-literature
Yang Xiaoyan X Wang Lei L Zhang Zihao Z Hu Jiayi J Liu Xiaoling X Wen Hao H Liu Minghao M Zhang Xue X Dai Hongyan H Ni Mei M Li Rui R Guo Rong R Zhang Lei L Luan Xiaorong X Lin Huili H Dong Mei M Lu Huixia H
Frontiers in cardiovascular medicine 20210528
<b>Background:</b> Atherosclerosis is closely associated with proliferation of the adventitial vasa vasorum, leading to the atherosclerotic plaque progression and vulnerability. In this report, we investigated the role of Ginsenoside Rb<sub>1</sub> (Rb<sub>1</sub>) on atherosclerotic plaque stabilization and adventitial vasa vasorum (VV) along with the mechanisms involved. <b>Methods and Results:</b> Apolipoprotein E-deficient (ApoE<sup>-/-</sup>) mice were fed with a high-fat diet for 20 weeks, ...[more]