Clinical value of NT-proBNP measurements in assessing patients in the pediatric intensive care unit.

ABSTRACT:

Background

N-terminal brain natriuretic peptide precursor (NT-proBNP) and brain natriuretic peptide (BNP) are mainly produced and secreted in the heart. In 2008, the European Heart Association recommended that serum BNP/NT-proBNP levels should be included in one of the diagnostic criteria of heart failure. Serum NT-proBNP is more stable than BNP, and the detection results are less affected by objective factors, so it is widely used. At present, NT-proBNP has long been beyond the scope of heart failure markers, and has a wide range of clinical value in the evaluation and prediction of some serious diseases. This study prospectively studied the predictive value of serum NT-proBNP in pediatric intensive care unit (PICU).

Methods

This was a prospective study involving 375 childr

SUBMITTER: Liu F 

PROVIDER: S-EPMC8192984 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature