Congenital diaphragmatic hernia: a narrative review of controversies in neonatal management.

ABSTRACT: The consequences of most hernias can be immediately corrected by surgical repair. However, this isn't always the case for children born with a congenital diaphragmatic hernia. The derangements in physiology encountered immediately after birth result from pulmonary hypoplasia and hypertension caused by herniation of abdominal contents into the chest early in lung development. This degree of physiologic compromise can vary from mild to severe. Postnatal management of these children remains controversial. Although heavily studied, multi-institutional randomized controlled trials are lacking to help determine what constitutes best practice. Additionally, the results of the many studies currently within the literature that have investigated differing aspect of care (i.e., inhaled nitric oxide,

SUBMITTER: Yang MJ 

PROVIDER: S-EPMC8192986 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature