Alterations in biochemical markers in adenovirus infection.

ABSTRACT:

Background

Analyze possible relationships between HAdV and markers for inflammation, specifically the C-reactive protein (CRP) and procalcitonin (PCT) tests, along with other haematological markers.

Methods

Retrospective study of 487 children presenting with fever and/or acute respiratory symptoms in the Paediatric Emergency Department. Analyses included viral presence/absence (both HAdV and other respiratory viruses) in respiratory exudates, CRP and PCT alterations in plasma, and haematological markers in whole blood.

Results

Viral load was >500 copies/10³ cells of HAdV in 127 cases (26.1%), of which 66 (52%, P<0.0001) had alterations in PCT, and 112 (88.1%, P<0.0001) in CRP. Haematological markers were similar either HAdV was present or not, although many

SUBMITTER: Gomez de Ona C 

PROVIDER: S-EPMC8193001 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature