Characterising the background incidence rates of adverse events of special interest for covid-19 vaccines in eight countries: multinational network cohort study.

ABSTRACT:

Objective

To quantify the background incidence rates of 15 prespecified adverse events of special interest (AESIs) associated with covid-19 vaccines.

Design

Multinational network cohort study.

Setting

Electronic health records and health claims data from eight countries: Australia, France, Germany, Japan, the Netherlands, Spain, the United Kingdom, and the United States, mapped to a common data model.

Participants

126 661 070 people observed for at least 365 days before 1 January 2017, 2018, or 2019 from 13 databases.

Main outcome measures

Events of interests were 15 prespecified AESIs (non-haemorrhagic and haemorrhagic stroke, acute myocardial infarction, deep vein thrombosis, pulmonary embolism, anaphylaxis, Bell's palsy, myocarditis or pericarditis, n

SUBMITTER: Li X 

PROVIDER: S-EPMC8193077 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature