Benchmarking two commonly used Saccharomyces cerevisiae strains for heterologous vanillin-β-glucoside production.

ABSTRACT: The yeast Saccharomyces cerevisiae is a widely used eukaryotic model organism and a key cell factory for production of biofuels and wide range of chemicals. From the broad palette of available yeast strains, the most popular are those derived from laboratory strain S288c and the industrially relevant CEN.PK strain series. Importantly, in recent years these two strains have been subjected to comparative "-omics" analyzes pointing out significant genotypic and phenotypic differences. It is therefore possible that the two strains differ significantly with respect to their potential as cell factories for production of specific compounds. To examine this possibility, we have reconstructed a de novo vanillin-β-glucoside pathway in an identical manner in S288c and CEN.PK strains. Ch

SUBMITTER: Strucko T 

PROVIDER: S-EPMC8193238 | biostudies-literature | 2015 Dec

REPOSITORIES: biostudies-literature