Analyzing redox balance in a synthetic yeast platform to improve utilization of brown macroalgae as feedstock.

ABSTRACT: Macroalgae have high potential to be an efficient, and sustainable feedstock for the production of biofuels and other more valuable chemicals. Attempts have been made to enable the co-fermentation of alginate and mannitol by Saccharomyces cerevisiae to unlock the full potential of this marine biomass. However, the efficient use of the sugars derived from macroalgae depends on the equilibrium of cofactors derived from the alginate and mannitol catabolic pathways. There are a number of strong metabolic limitations that have to be tackled before this bioconversion can be carried out efficiently by engineered yeast cells. An analysis of the redox balance during ethanol fermentation from alginate and mannitol by Saccharomyces cerevisiae using metabolic engineering tools was carrie

SUBMITTER: Contador CA 

PROVIDER: S-EPMC8193247 | biostudies-literature | 2015 Dec

REPOSITORIES: biostudies-literature