Bilateral Chilblain-like Lesions of the Toes Characterized by Microvascular Remodeling in Adolescents During the COVID-19 Pandemic.

ABSTRACT:

Importance

Chilblain-like lesions have been one of the most frequently described cutaneous manifestations during the COVID-19 pandemic. Their etiopathogenesis, including the role of SARS-CoV-2, remains elusive.

Objective

To examine the association of chilblain-like lesions with SARS-CoV-2 infection.

Design, setting, and participants

This prospective case series enrolled 17 adolescents who presented with chilblain-like lesions from April 1 to June 30, 2020, at a tertiary referral academic hospital in Italy.

Main outcomes and measures

Macroscopic (clinical and dermoscopic) and microscopic (histopathologic) analysis contributed to a thorough understanding of the lesions. Nasopharyngeal swab, serologic testing, and in situ hybridization of the skin biopsy specimens

SUBMITTER: Discepolo V 

PROVIDER: S-EPMC8193438 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature