How do children with autism spectrum disorder form gist memory during sleep? A study of slow oscillation-spindle coupling.

ABSTRACT: Sleep is assumed to support memory through an active systems consolidation process that does not only strengthen newly encoded representations but also facilitates the formation of more abstract gist memories. Studies in humans and rodents indicate a key role of the precise temporal coupling of sleep slow oscillations (SO) and spindles in this process. The present study aimed at bolstering these findings in typically developing (TD) children, and at dissecting particularities in SO-spindle coupling underlying signs of enhanced gist memory formation during sleep found in a foregoing study in children with autism spectrum disorder (ASD) without intellectual impairment. Sleep data from 19 boys with ASD and 20 TD boys (9-12 years) were analyzed. Children performed a picture-recognition task an

SUBMITTER: Kurz EM 

PROVIDER: S-EPMC8193554 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature