Awake delta and theta-rhythmic hippocampal network modes during intermittent locomotor behaviors in the rat.

ABSTRACT: Delta-frequency network activity is commonly associated with sleep or behavioral disengagement accompanied by a dearth of cortical spiking, but delta in awake behaving animals is not well understood. We show that hippocampal (HC) synchronization in the delta frequency band (1-4 Hz) is related to animals' locomotor behavior using detailed analyses of the HC local field potential (LFP) and simultaneous head- and body-tracking data. In contrast to running-speed modulation of the theta rhythm (6-10 Hz), delta was most prominent when animals were stationary or moving slowly, that is, when theta and fast gamma (65-120 Hz) were weak, and often developed rapidly when animals paused briefly between runs. We next combined time-frequency decomposition of the LFP with hierarchical clustering algorithm

SUBMITTER: Schultheiss NW 

PROVIDER: S-EPMC8193833 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature