Dengue fever and insecticide resistance in Aedes mosquitoes in Southeast Asia: a review.

ABSTRACT: Dengue fever is the most important mosquito-borne viral disease in Southeast Asia. Insecticides remain the most effective vector control approach for Aedes mosquitoes. Four main classes of insecticides are widely used for mosquito control: organochlorines, organophosphates, pyrethroids and carbamates. Here, we review the distribution of dengue fever from 2000 to 2020 and its associated mortality in Southeast Asian countries, and we gather evidence on the trend of insecticide resistance and its distribution in these countries since 2000, summarising the mechanisms involved. The prevalence of resistance to these insecticides is increasing in Southeast Asia, and the mechanisms of resistance are reported to be associated with target site mutations, metabolic detoxification, reduced penetration

SUBMITTER: Gan SJ 

PROVIDER: S-EPMC8194039 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature